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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BIRC5
All Species:
16.97
Human Site:
S88
Identified Species:
41.48
UniProt:
O15392
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15392
NP_001012270.1
142
16390
S88
S
S
G
C
A
F
L
S
V
K
K
Q
F
E
E
Chimpanzee
Pan troglodytes
XP_512010
142
16317
S88
S
S
G
C
A
F
L
S
V
K
K
Q
F
E
E
Rhesus Macaque
Macaca mulatta
XP_001108164
142
16287
S88
S
S
G
C
A
F
L
S
V
K
K
Q
F
E
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O70201
140
16279
T88
S
P
G
C
A
F
L
T
V
K
K
Q
M
E
E
Rat
Rattus norvegicus
Q9JHY7
142
16674
T88
S
P
G
C
A
F
L
T
V
K
K
Q
V
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517041
145
16221
A91
S
P
G
C
A
F
V
A
L
K
K
K
I
E
D
Chicken
Gallus gallus
NP_001012318
142
15926
A90
S
A
G
C
A
F
A
A
L
Q
K
D
P
S
N
Frog
Xenopus laevis
Q50L39
157
18311
A101
S
P
S
C
L
F
I
A
L
K
K
K
A
E
E
Zebra Danio
Brachydanio rerio
NP_919378
142
16393
L87
S
P
S
C
D
F
I
L
L
K
K
T
V
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796206
147
17303
K96
A
P
K
C
P
F
I
K
H
W
K
P
E
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
97.8
N.A.
N.A.
82.3
82.3
N.A.
57.2
59.1
51.5
49.2
N.A.
N.A.
N.A.
N.A.
44.2
Protein Similarity:
100
99.3
98.5
N.A.
N.A.
91.5
90.8
N.A.
72.4
73.2
66.8
64
N.A.
N.A.
N.A.
N.A.
65.3
P-Site Identity:
100
100
100
N.A.
N.A.
80
80
N.A.
53.3
40
46.6
33.3
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
100
100
N.A.
N.A.
86.6
86.6
N.A.
86.6
66.6
73.3
53.3
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
70
0
10
30
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
0
0
10
0
10
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
10
80
70
% E
% Phe:
0
0
0
0
0
100
0
0
0
0
0
0
30
0
0
% F
% Gly:
0
0
70
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
30
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
10
0
0
0
0
10
0
80
100
20
0
0
0
% K
% Leu:
0
0
0
0
10
0
50
10
40
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
60
0
0
10
0
0
0
0
0
0
10
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
50
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
90
30
20
0
0
0
0
30
0
0
0
0
0
10
10
% S
% Thr:
0
0
0
0
0
0
0
20
0
0
0
10
0
0
0
% T
% Val:
0
0
0
0
0
0
10
0
50
0
0
0
20
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _